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arid1a protein, human
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
No genes found
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Pathway Enrichment
Most Correlated Biogroups
No biogroups found
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Curated Studies
Most Correlated Studies
Ovarian clear cell carcinoma TOV-21G cells with ARID1A mutation and resistant to GSK126
Ewing's sarcoma TC-32 and A-4573 cells with shRNA-mediated EWS-FLI1 and ARID1A knockdown
ARID1A knockdown in OE33 esophageal adenocarcinoma cells
Colorectal cancer HCT116 wildtype or ARID1A knockout cells after shRNA knockdown of ARID1B
Hepatocellular carcinoma HepG2 cells with siRNA knockdowns or ARID1A, ARID1B, or ARID2
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Literature
Most Relevant Literature
Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties…
Comparative analysis of ARID1A mutations with mRNA levels and protein expression in gastric carcinom…
Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Frameshift mutation and inactivation of ARID1A in an epithelioid sarcoma.
ARID1A mutations in cancer development: mechanism and therapy.
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Clinical Trials
Most Relevant Clinical Trials
Phase II Study of Tazemetostat in Solid Tumors Harboring an ARID1A Mutation
Tremelimumab, Durvalumab, and Belinostat for the Treatment of ARID1A Mutated Metastatic or Unresecta…
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid T…
M6620 (VX-970) in Selected Solid Tumors
Preoperative Olaparib Endometrial Carcinoma Study (POLEN)
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