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azd8055
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Summary
General Info
Genetic Markers
Most Correlated Genes
RBP4
STEAP1
HOXC10
AKAP12
WIF1
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Pathway Enrichment
Most Correlated Biogroups
cytosol
regulation of nitrogen compound metabolic process
organic cyclic compound binding
heterocyclic compound binding
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Melanoma Me13 cells treated with MEK1/2, PI3K/mTOR, mTOR, and BRAF V600E inhibitors
L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Anti-tumor effect of AZD8055 against bladder cancer and bladder cancer-associated macrophages.
In Vitro and In Vivo Interactions of TOR Inhibitor AZD8055 and Azoles against Pathogenic Fungi.
AZD8055 enhances in vivo efficacy of afatinib in chordomas.
Comparison of dual mTORC1/2 inhibitor AZD8055 and mTORC1 inhibitor rapamycin on the metabolism of br…
Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular…
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Clinical Trials
Most Relevant Clinical Trials
AZD8055 for Adults With Recurrent Gliomas
Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055
A Study of Tor Kinase Inhibitor in Advanced Tumors
Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours
Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Live…
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