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benzbromarone
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Summary
General Info
Genetic Markers
Most Correlated Genes
Acot1
ACOT2
TOP2A
TEX49
PBK
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Pathway Enrichment
Most Correlated Biogroups
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DODD_NASOPHARYNGEAL_CARCINOMA_DN
organic cyclic compound binding
heterocyclic compound binding
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
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Curated Studies
Most Correlated Studies
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Identification of CYP isozymes involved in benzbromarone metabolism in human liver microsomes.
Benzbromarone stabilizes ΔF508 CFTR at the cell surface.
Metabolism studies of benzbromarone in rats by high performance liquid chromatography-quadrupole tim…
Benzbromarone: a double-edged sword that cuts the liver?
The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.
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Clinical Trials
Most Relevant Clinical Trials
Acute Effects of Benzbromaron on the Pulmonary Circulation
Compare the Renal Protective Effects of Febuxostat and Benzbromarone
Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients
Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction
Evaluate the Efficacy and Safety of D-0120 in Primary Hyperuricemia Patients
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