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blood coagulation factor inhibitors
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
F5
F8
SERPINE1
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Pathway Enrichment
Most Correlated Biogroups
Coagulation factor 5/8-like
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_
Multicopper oxidase, type 3
Multicopper oxidases, conserved site
HALLMARK_COMPLEMENT
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Curated Studies
Most Correlated Studies
Blood of patients with septic shock before and after treatment with activated protein C agent Xigris
Drug target sets for approved compounds
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
L1000 CMAP - Lung cancer A549 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Cumulative inhibitor incidence in previously untreated patients with severe hemophilia A treated wit…
Progressing towards optimal management of haemophilia A patients with inhibitors. Foreword.
Successful management of a possible antibiotic-related acquired factor V inhibitor: a case report an…
How I manage patients with acquired haemophilia A.
Management of bleeding disorders in children.
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Clinical Trials
Most Relevant Clinical Trials
Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension
Clinical Study of Recombinant Human Activated Coagulation Factor VII for Injection in Patients With …
Pharmacokinetics Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemoph…
Coagulation Factor Changes Associated With Postpartum Hysterectomies
A Study to Evaluate the Pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc Fusion Prot…
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