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buthionine sulfoximine
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
RGD1309362
CD24
HAO2
Cyp2c12
EIF4E3
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Pathway Enrichment
Most Correlated Biogroups
nucleoplasm
PILON_KLF1_TARGETS_DN
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
regulation of nitrogen compound metabolic process
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Affymetrix]
Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Codelink]
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Literature
Most Relevant Literature
Cardiovascular and renal manifestations of glutathione depletion induced by buthionine sulfoximine.
Promising effects of the 4HPR-BSO combination in neuroblastoma monolayers and spheroids.
Role of sympathetic tone in BSO-induced hypertension in mice.
Fluoride-induced genotoxicity in mouse bone marrow cells: effect of buthionine sulfoximine and N-ace…
Sex difference in susceptibility to acetaminophen hepatotoxicity is reversed by buthionine sulfoximi…
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Clinical Trials
Most Relevant Clinical Trials
N99-02: Melphalan and Buthionine Sulfoximine
A Phase I Trial of Normothermic Isolated Limb Infusion (ILI) With Melphalan Plus Buthionine Sulfoxim…
Chemotherapy in Treating Children With Neuroblastoma
Systemic Glutathione Level in Normal Tension Glaucoma
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