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(e.g. rs4950928, GATA1, Angiogenesis, Obesity, Retina, Human chorionic gonadotropin)
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QuickView for canertinib (compound)


Genetic Markers

Most Correlated Genes

  1. WIF1
  2. GPX3
  3. HBB
  4. COL11A1
  5. RBP4
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. regulation of nitrogen compound metabolic process
  3. organic cyclic compound binding
  4. heterocyclic compound binding
  5. vesicle
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  3. L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
  4. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  5. L1000 CMAP - Prostate cancer LNCAP cells treated with small molecule perturbagens
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Literature

Most Relevant Literature

  1. Canertinib induces ototoxicity in three preclinical models.
  2. Role of empirical isolation of the superior vena cava in patients with recurrence of atrial fibrilla…
  3. Effective degradation of EGFRL858R+T790M mutant proteins by CRBN-based PROTACs through both proteoso…
  4. Leflunomide treatment for patients hospitalised with COVID-19: DEFEAT-COVID randomised controlled tr…
  5. Association of ward-level antibiotic consumption with healthcare-associated Clostridioides difficile…
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Clinical Trials

Most Relevant Clinical Trials

  1. Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subpr…
  2. A Phase 2, Randomized, Open-Label Study Of Single Agent CI-1033 In Patients With Advanced Non-Small …
  3. A Phase II Study of CI-1033 in Treating Patients With Metastatic (Stage IV) Breast Cancer
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