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caspase 10
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Genetic Markers
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Curated Studies
Most Correlated Studies
Lymphoma U937 cells with CRISPR mediated IRF2 gene knockout and rescue by IRF2 overexpression
Bone marrow derived macrophages from RIPK3 and or CASP8 knockout mice treated with LPS
Non-small cell lung cancer NCI-H1299 cells treated with mercury chloride
Lungs of Casp11 or Gsdmd knockout mice intranasally infected with SARS-CoV-2 MA10 strain
Blood tissues of NLRC4-MAS and NOMID patients undergoing anakinra therapy
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Literature
Most Relevant Literature
An upstream initiator caspase 10 of snakehead murrel Channa striatus, containing DED, p20 and p10 su…
Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-…
RIOK3 interacts with caspase-10 and negatively regulates the NF-kappaB signaling pathway.
Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway.
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.
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Clinical Trials
Most Relevant Clinical Trials
Caspase Inhibition in Islet Transplantation
Role of Tyrosine Kinase Lyn and Cleaved Form by Caspases in Psoriasis
Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
Emricasan, an Oral Caspase Inhibitor, in Subjects With Non-Alcoholic Steatohepatitis (NASH) Cirrhosi…
Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension
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