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cdk4 protein, human
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
HeLa cells after G0-G1 / G1-S arrest release with CDK4/6 shRNA and IL-1a treated
Cyclin D1 and CDK4 contribute to the undifferentiated phenotype in neuroblastoma
Mantle cell lymphoma in Cdk4R24C c-myc-3’RR transgenic mice
T-ALL cell line KOPTK1 treated with CDK4/6 inhibitor PD 0332991
Breast cancer V720 cells treated with CDK4/6 inhibitor PD 0332991
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Literature
Most Relevant Literature
lncRNA TPT1‑AS1 knockdown inhibits liver cancer cell proliferation, migration and invasion.
Ribociclib: First Global Approval.
α-Lipoic acid inhibits human lung cancer cell proliferation through Grb2-mediated EGFR downregulatio…
CyclinD-CDK4/6 complexes phosphorylate CDC25A and regulate its stability.
Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine Cyclin…
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Clinical Trials
Most Relevant Clinical Trials
Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Br…
First-in Human (FIH) Trial of ETH-155008 in Subjects With B-NHL, CLL/SLL and AML
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Subjects With Ho…
Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Enc…
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