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QuickView for chek1 protein, human (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. Breast adenocarcinoma MDA-MB-231 cells with knockdown of TRA2a and TRA2b
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Literature

Most Relevant Literature

  1. Genetic variants in CHEK1 gene are associated with the prognosis of thoracic esophageal squamous cel…
  2. Dietary flavonoid derivatives enhance chemotherapeutic effect by inhibiting the DNA damage response …
  3. Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in rel…
  4. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.
  5. The Chk1 inhibitor MK-8776 increases the radiosensitivity of human triple-negative breast cancer by …
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Clinical Trials

Most Relevant Clinical Trials

  1. AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma
  2. Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes
  3. Nivolumab and Veliparib in Treating Patients With Recurrent or Refractory Stage IV Solid Tumors That…
  4. Olaparib in Treating Patients With Metastatic or Advanced Urothelial Cancer With DNA-Repair Defects
  5. A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.
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