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Correlation Engine 2.0
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QuickView for ci 994 (compound)


Genetic Markers

Most Correlated Genes

  1. RSAD2
  2. SELENOP
  3. CALCA
  4. CDKN1B
  5. Pisd-ps3
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Pathway Enrichment

Most Correlated Biogroups

  1. WONG_ADULT_TISSUE_STEM_MODULE
  2. cell periphery
  3. ZHANG_TLX_TARGETS_60HR_UP
  4. cell differentiation
  5. NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN
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Curated Studies

Most Correlated Studies

  1. Pancreatic cell lines treated with chromatin-targeting small molecules
  2. Brain regions of mice treated with HDAC inhibitors CDP-60, SAHA or CI-994
  3. Hippocampi of mice; effects of CI-994 on memory extinction upon contextual fear conditioning
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Literature

Most Relevant Literature

  1. Combination Treatment of CI-994 With Etoposide Potentiates Anticancer Effects Through a Topoisomeras…
  2. The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular …
  3. Dose Effects of Histone Deacetylase Inhibitor Tacedinaline (CI-994) on Antipsychotic Haloperidol-Ind…
  4. Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal d…
  5. Class I HDAC imaging using [ (3)H]CI-994 autoradiography.
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Clinical Trials

Most Relevant Clinical Trials

  1. Gemcitabine With or Without CI-994 in Treating Patients With Advanced Non-small Cell Lung Cancer
  2. Gemcitabine With or Without CI-994 in Treating Patients With Advanced Pancreatic Cancer
  3. CI-994 in Treating Patients With Advanced Myeloma
  4. A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who R…
  5. Observational Study of the Prevalence of CCSVI in Multiple Sclerosis and in Other Neurodegenerative …
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