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class i histone deacetylases
(compound)
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Genetic Markers
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Most Correlated Studies
Broad Connectivity Map (CMAP 2.0) compound database
Brain regions of mice treated with HDAC inhibitors CDP-60, SAHA or CI-994
Breast cancer MCF7 cells treated with sphingosine-1-phosphate, FTY720 or SAHA
Prostate cancer cells exposed to normoxia or hypoxia and treated with HDAC inhibitor vorinostat
Breast adenocarcinoma MDA-MB-231 cells treated with SAHA and Pargyline
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Literature
Most Relevant Literature
Targeting class I histone deacetylases in cancer therapy.
Elevated immunoreactivity against class I histone deacetylases in adenomyosis.
Class I histone deacetylase activity is required for proliferation of renal epithelial cells.
Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.
Molecular mechanisms associated with the antidepressant effects of the class I histone deacetylase i…
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Clinical Trials
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Imaging Histone Deacetylase in the Heart
Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)
Safety and Efficacy of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherap…
Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours
Anti-PD-1 Antibody Combined With Histone Deacetylase Inhibitor in Patients With Advanced Cervical Ca…
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