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complement system proteins
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Genetic Markers
Most Correlated Genes
PLPP3
TNFSF15
LDLR
INHBA
SLAMF7
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
PILON_KLF1_TARGETS_DN
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP
regulation of nitrogen compound metabolic process
GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP
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Curated Studies
Most Correlated Studies
Polymorphonuclear leukocytes (PMNs) and PBMCs of Job's patients incubated with IgG and C3bi beads
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
L1000 CMAP - Adenocarcinoma of breast MCF7 cells treated with ligand perturbagens
L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
Retinal pigment epithelium cells from iPSC stem cells treated with complement competent serum
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Literature
Most Relevant Literature
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis.
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi-protein casc…
Complement Proteins in Serum Astrocyte-Derived Exosomes Are Associated with Poststroke Cognitive Imp…
Associations of cerebrospinal fluid complement proteins with Alzheimer's pathology, cognition, and b…
Complement proteins are elevated in blood serum but not CSF in clinical high-risk and antipsychotic-…
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Clinical Trials
Most Relevant Clinical Trials
Complement Activation in the Lysosomal Storage Disorders
Complement and Graft-versus-host Disease
Complement Inhibition in aHUS Dialysis Patients
Complement Diagnosis of Acute Appendicitis
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers
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