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complement system proteins
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Genetic Markers
Most Correlated Genes
PLPP3
TNFSF15
LDLR
INHBA
SLAMF7
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
PILON_KLF1_TARGETS_DN
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP
regulation of nitrogen compound metabolic process
GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP
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Curated Studies
Most Correlated Studies
C1q elicited macrophage gene expression
Leukemic cells' transcriptomic profiles in response to decreased TNFa expression
Blood of C5 deficient patient in response to E. coli with complement and CD14 inhibition
Macrophages treated with oxidized or acetylated low-density lipoprotein and complement protein C1q
Retinal pigment epithelium cells from iPSC stem cells treated with complement competent serum
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Literature
Most Relevant Literature
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi-protein casc…
Complement proteins are elevated in blood serum but not CSF in clinical high-risk and antipsychotic-…
The Nano-War Against Complement Proteins.
Urinary complement proteins in IgA nephropathy progression from a relative quantitative proteomic an…
The effects of exercise on complement system proteins in humans: a systematic scoping review.
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Clinical Trials
Most Relevant Clinical Trials
Complement Activation in the Lysosomal Storage Disorders
Complement and Graft-versus-host Disease
Complement Inhibition in aHUS Dialysis Patients
Complement Diagnosis of Acute Appendicitis
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers
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