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cx 4945
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
BAAT
OPRD1
LEFTY1
KCNB1
NPC1L1
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Pathway Enrichment
Most Correlated Biogroups
cytosol
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
nucleoplasm
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
Breast cancer MB-468 cells treated with CX4945 compound
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Anti-adipogenic and Pro-lipolytic Effects on 3T3-L1 Preadipocytes by CX-4945, an Inhibitor of Casein…
CX-4945 inhibits fibroblast-like synoviocytes functions through the CK2-p53 axis to reduce rheumatoi…
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, a…
Sequence of CX-4945 and Cisplatin Administration Determines the Effectiveness of Drug Combination an…
The Casein Kinase 2 Inhibitor CX-4945 Promotes Cholangiocarcinoma Cell Death Through PLK1.
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Clinical Trials
Most Relevant Clinical Trials
A Study of Silmitasertib (CX-4945) in Healthy Subject
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or…
Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangioc…
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcin…
Dose-escalation Study of Oral CX-4945
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