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cyclin- dependent kinase 2
Summary
General Info
Curated Studies
Most Correlated Studies
T cell acute lymphoblastic leukemia MOLT4 cells treated with cyclin-dependent kinase inhibitors
NSCLC PC9 cells selected for gefitinib sensitivity or resistance treated with EGF and gefitinib
Prostate cancer cell line (LNCaP) treated with trichostatin A or roscovitine, or EZH2 knockdown
Breast cancer MCF-7 cells with Abemaciclib and SR11302
Acute myeloid leukemia MV4-11 cells treated with BSJ-03-123, YKL-06-102 and palbociclib
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Literature
Most Relevant Literature
An overview of CDK3 in cancer: clinical significance and pharmacological implications.
CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses.
Cdk2 suppresses IL-23 expression and the onset of severe acute pancreatitis.
Discovery of novel CDK2 inhibitors using multistage virtual screening and in vitro melanoma cell lin…
Over-expression of NUDT21 inhibits the proliferation of HCT-116 colon cancer cells via blocking P53/…
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Clinical Trials
Most Relevant Clinical Trials
A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Adva…
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder
Evaluation of Skin Health and Quality of Life in Patients Receiving Anti-PD1/PDL1/CTLA4 or Cyclin-de…
A Phase 1 Study Of An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In Patients With …
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