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QuickView for dexrazoxane (compound)


Genetic Markers

Most Correlated Genes

  1. TOP2A
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Pathway Enrichment

Most Correlated Biogroups

  1. DNA topoisomerase, type IIA
  2. DNA topoisomerase, type IIA, conserved site
  3. DNA topoisomerase II, eukaryotic-type
  4. DNA topoisomerase, type IIA-like domain superfamily
  5. DNA topoisomerase, type IIA, subunit B, C-terminal
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Curated Studies

Most Correlated Studies

  1. Drug target sets for approved compounds
  2. HTETOP cells following doxycycline or dexrazoxane treatment
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Literature

Most Relevant Literature

  1. Savene® (dexrazoxane) use in clinical practice.
  2. Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity.
  3. Dexrazoxane use in pediatric patients with acute lymphoblastic or myeloid leukemia from 1999 and 200…
  4. Use of the cardioprotectants thymosin β4 and dexrazoxane during congenital heart surgery: proposal f…
  5. Cardioprotective effect of early dexrazoxane use in anthracycline treated pediatric patients.
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Clinical Trials

Most Relevant Clinical Trials

  1. Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
  2. Dexrazoxane as a Protective Agent in Anthracycline Treated Breast Cancer
  3. Dexrazoxane and Cisplatin in Treating Patients With Advanced Solid Tumors
  4. Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
  5. Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease
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