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dnmt1 protein, human
(compound)
Summary
General Info
Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Colorectal cancer HCT-116 cells with double knockout of DNMT1A and DNMT3B genes treated with EGF
DNMT1 Maintains Progenitor Function in Self-Renewing Somatic Tissue
Multiple myeloma MM.1S cells with HDAC3 or DNMT1 shRNA knockdown
Embryonic stem cells with DNMT1/DNMT3a/DNMT3b triple knockout and/or HP1a/HP1b/HP1g depletion
AtT-20 cells following Dnmt1 knockdown
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Literature
Most Relevant Literature
Functional role of DNMT1 in the anti-leukemic effects of hypomethylating agents in AML cells.
Knockdown of sirtuin6 positively regulates acetylation of DNMT1 to inhibit NOTCH signaling pathway i…
Casticin Attenuates Stemness in Cervical Cancer Stem-Like Cells by Regulating Activity and Expressio…
Histone H3 Inhibits Ubiquitin-Ubiquitin Intermolecular Interactions to Enhance Binding to DNA Methyl…
Exosomal DNMT1 mRNA transcript is elevated in acute lymphoblastic leukemia which might reprograms le…
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Clinical Trials
Most Relevant Clinical Trials
Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)
p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer
A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjec…
DNA Methylation and Perioperative Pain Treatment
Rational EpigenetiC Immunotherapy for SEcond Line Therapy in Patients With NSCLC: PRECISE Trial
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