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dnmt1 protein, human
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Genetic Markers
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No genes found
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Pathway Enrichment
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No biogroups found
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Curated Studies
Most Correlated Studies
DNMT1 Maintains Progenitor Function in Self-Renewing Somatic Tissue
Multiple myeloma MM.1S cells with HDAC3 or DNMT1 shRNA knockdown
AtT-20 cells following Dnmt1 knockdown
Embryonic stem cells with DNMT1/DNMT3a/DNMT3b triple knockout and/or HP1a/HP1b/HP1g depletion
Breast adenocarcinoma MCF7 cells treated with 6-thioguanine
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Literature
Most Relevant Literature
Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia as a Presentation of a Novel DNMT1 Mutation.
Fragment-based discovery of new potential DNMT1 inhibitors integrating multiple pharmacophore modeli…
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing D…
An ultra-sensitive CRISPR-Cas12a and aptamer-based biosensor utilizing Entropy-driven catalytic DNA …
Milk derived extracellular vesicle uptake in human microglia regulates the DNA methylation machinery…
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Clinical Trials
Most Relevant Clinical Trials
Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)
p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Pred…
A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjec…
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma
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