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drotrecogin alfa activated
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
F5
F8
SERPINE1
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Pathway Enrichment
Most Correlated Biogroups
Coagulation factor 5/8-like
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_
Multicopper oxidase, type 3
Multicopper oxidases, conserved site
HALLMARK_COMPLEMENT
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Curated Studies
Most Correlated Studies
Blood of patients with septic shock before and after treatment with activated protein C agent Xigris
Drug target sets for approved compounds
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Literature
Most Relevant Literature
Effectiveness and safety of drotrecogin alfa (activated) for severe sepsis: a meta-analysis and meta…
Drotrecogin alfa (activated)...a sad final fizzle to a roller-coaster party.
Drotrecogin alfa (activated) in adults with septic shock.
The rise and fall of drotrecogin alfa (activated).
A multicenter evaluation of the safety of drotrecogin alfa (activated) in patients with baseline ble…
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Clinical Trials
Most Relevant Clinical Trials
Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion
A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa…
The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients With Severe Sepsis
The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Deat…
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