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endothelin
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
LOC285556
CCL4
CCL3
MAFF
SERPINE1
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Pathway Enrichment
Most Correlated Biogroups
FISCHER_DREAM_TARGETS
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP
DODD_NASOPHARYNGEAL_CARCINOMA_DN
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Curated Studies
Most Correlated Studies
Cardiomyocytes (iPS derived) treated with glucose, endothelin-1 and cortisol
Ventricular cardiomyocytes derived from human iPSC stimulated with endothelin-1
Retinal ganglion cells treated with endothelian ET-1, ET-2 or ET-3
Mouse dermal fibroblasts treated with endothelin-1
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Elevated renal afferent nerve activity in a rat model of endothelin B receptor deficiency.
Porphyromonas gingivalis infection upregulates the endothelin (ET) system in brain microvascular end…
Endothelin ETB Receptor-Mediated Astrocytic Activation: Pathological Roles in Brain Disorders.
Gestational intermittent hypoxia induces endothelial dysfunction and hypertension in pregnant rats: …
Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer.
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Clinical Trials
Most Relevant Clinical Trials
The Role of Endothelin in the Supine Hypertension of Autonomic Failure
The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction
Observational Endothelin and Markers of Cellular Apoptosis In CSF Head Injury
The Contribution of Endothelin to Vasomotor Function in Diseased Coronary Arteries
Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI
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