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QuickView for f8 protein, human (compound)


Genetic Markers

Most Correlated Genes

  1. SPP1
  2. APOC1
  3. RAB3IL1
  4. EGR3
  5. LINC00487
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Pathway Enrichment

Most Correlated Biogroups

  1. RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
  2. GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP
  3. GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN
  4. GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP
  5. GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP
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Curated Studies

Most Correlated Studies

  1. Macrophages from monocytes of donors treated with FVIII or FVIII-Fc fusion protein
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Literature

Most Relevant Literature

  1. Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII…
  2. Hemophilia A ameliorated in mice by CRISPR-based in vivo genome editing of human Factor VIII.
  3. A Generative and Causal Pharmacokinetic Model for Factor VIII in Hemophilia A: A Machine Learning Fr…
  4. Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances express…
  5. Canadian clinical experience on switching from standard half-life recombinant factor VIII (rFVIII), …
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study of BAX 888 in Male Adults With Severe Hemophilia A
  2. Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients
  3. Personalized Prediction of Tolerance and Immunogenicity in Hemophilia
  4. Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
  5. Hemlibra in Mild Hemophilia A
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