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folic acid antagonists
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
DHFR
TYMS
PLAU
TUBA1A
FAS
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Pathway Enrichment
Most Correlated Biogroups
PILON_KLF1_TARGETS_DN
PUJANA_BRCA1_PCC_NETWORK
regulation of nitrogen compound metabolic process
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
cytosol
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Curated Studies
Most Correlated Studies
Diffuse large B cell lymphomas from brains of primary CNS lymphoma patients
PBMCs and granulocytes from post-remission juvenile idiopathic arthritis patients
Hybridoma EA.hy926 cells grown in low or normal folate levels and treated with methotrexate (MTX)
Hepatocellular carcinoma HepG2 cells, a model of drug induced liver injury
Diffuse Large B-Cell Lymphoma OCI-LY3 cells time-course/dose response treatment with 14 drug panel
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Literature
Most Relevant Literature
New Insights into Antimalarial Chemopreventive Activity of Antifolates.
The Pup-Proteasome System Protects Mycobacteria from Antimicrobial Antifolates.
Interaction mechanism of novel fluorescent antifolates targeted with folate receptors α and β via mo…
Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade se…
A γ-glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in a…
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Clinical Trials
Most Relevant Clinical Trials
Folic Acid and Intensive Antihypertensive Therapy for Hypertension With CSVD
Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth
Folic Acid Supplementation in Gambian Primigravidae
High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention
The Effect of High Dose Folic Acid Versus Placebo on the Rate of Gestational Diabetes or Gestational…
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