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foxp3 protein, human
(compound)
Summary
General Info
Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Natural and induced regulatory T cells from FOXP3 knockout and wildtype mice
CD4+ T cells compared based on activation state, suppressor phenotype and FOXP3 expression
T-cells with FOXP3 siRNA knockdown and activated with anti-CD2/CD3/CD28 antibodies + IL2
Regulatory T (Treg) cells and conventional T cells reponses to different factors and conditions
CD4+ T cells expressing chimeric antigen receptors (CAR) against mesothelin; varying signal domains
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Literature
Most Relevant Literature
Immune dysregulation, polyendocrinopathy and enteropathy, X-linked (IPEX) syndrome due to a mutation…
Development and function of FOXP3+ regulators of immune responses.
Epigenetic and immunological indicators of IPEX disease in subjects with FOXP3 gene mutation.
Restoration of established systemic inflammation and autoimmunity by Foxp3+ regulatory T cells.
High density of FOXP3 predicts better prognosis in germinal and non-germinal centre diffuse large B-…
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Clinical Trials
Most Relevant Clinical Trials
Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Sp…
DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patie…
Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NA…
The Role of FGL2-FcgammaRIIB Inhibitory Pathway in Human Viral Hepatitis
A Phase I, Dose-Escalation Study to Assess the Safety and Biological Activity of Recombinant Human I…
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