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QuickView for gaba antagonist (compound)


Genetic Markers

Most Correlated Genes

  1. TAGLN
  2. FOS
  3. FOSB
  4. CYP51A1
  5. GABRA1
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. response to organic substance
  3. heterocyclic compound binding
  4. organic cyclic compound binding
  5. cell differentiation
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Curated Studies

Most Correlated Studies

  1. Striata treated with psychotropic drugs - Timecourse
  2. GSE46864_SE_R_Gabazine treatment of hippocampal organotypic cultures
  3. Cerebellar after ventral hippocampal lesion or tetrodotoxin disruption, or neuroleptics trea
  4. Liver tissues from rats after treatment with different compounds
  5. Livers from rats exposed to chemicals with different mechanisms of action
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Literature

Most Relevant Literature

  1. 5-(4-Pyridinyl)-3-isothiazolols as Competitive Antagonists of Insect GABA Receptors: Design, Synthes…
  2. Regulation of the central amygdala on intestinal motility and behavior via the lateral hypothalamus …
  3. Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the …
  4. The Relative Contribution of Glycine-GABA Cotransmission in the Core of the Respiratory Network.
  5. Long-term potentiation is differentially expressed in rostral and caudal neurons in the superior cer…
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Clinical Trials

Most Relevant Clinical Trials

  1. GABA Antagonist to Improve Reversal of Anesthesia With High-density EEG Surveillance
  2. Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus
  3. Treatment of Hepatic Encephalopathy With Flumazenil and Change in Cortical GABA Levels in MRS
  4. Visceral Afferents
  5. Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency
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