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QuickView for guanine nucleotides (compound)


Genetic Markers

Most Correlated Genes

  1. IFIT2
  2. PTGS2
  3. CCL2
  4. IFIT1
  5. IL6
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Pathway Enrichment

Most Correlated Biogroups

  1. NUYTTEN_EZH2_TARGETS_UP
  2. HALLMARK_TNFA_SIGNALING_VIA_NFKB
  3. HALLMARK_INTERFERON_GAMMA_RESPONSE
  4. GSE42021_TREG_VS_TCONV_PLN_UP
  5. FOSTER_TOLERANT_MACROPHAGE_DN
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Curated Studies

Most Correlated Studies

  1. Lung epithelial cells treated with an RIG-I agonist or INFa-2b
  2. Acute myelomonocytic leukemia xenografts from marrow, blood, and spleen after LY2510924 treatment
  3. Dendritic cell stimulationed with 5 ligands over 9 time points
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Literature

Most Relevant Literature

  1. Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors…
  2. Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function.
  3. Guanine nucleotides differentially modulate backbone dynamics of the STAS domain of the SulP/SLC26 t…
  4. A small molecule-regulated guanine nucleotide exchange factor.
  5. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and p…
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Clinical Trials

Most Relevant Clinical Trials

  1. Effect of FAS and FAS Ligand Polymorphisms on Patients With Platinum-Based -Treated Malignant Pleura…
  2. Study of Circulating Tumoral DNA in Metastatic Choroidal Melanoma
  3. A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors
  4. An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
  5. Genomic Response Analysis of Heart Failure Therapy in African Americans
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