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haemolytic uraemic syndrome
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
CD46
CFH
C1GALT1C1
C3
CFB
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
REACTOME_REGULATION_OF_COMPLEMENT_CASCADE
REACTOME_COMPLEMENT_CASCADE
regulation of complement activation
complement activation
protein activation cascade
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Curated Studies
Most Correlated Studies
CD4+ T cells from an atypical hemolytic uremic syndrome (aHUS) patient carrying mutant CD46
CD8+ T cells from blood of CD46-deficient patients activated with antibodies against CD3 and CD46
OMIM - Hemolytic uremic syndrome
OMIM - Anemia
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Literature
Most Relevant Literature
Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: a focus on eculizu…
Monitoring and modeling treatment of atypical hemolytic uremic syndrome.
Familial atypical hemolytic uremic syndrome: a review of its genetic and clinical aspects.
Neonatal onset atypical hemolytic uremic syndrome successfully treated with eculizumab.
Neurologic involvement in atypical hemolytic uremic syndrome and successful treatment with eculizuma…
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Clinical Trials
Most Relevant Clinical Trials
Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects
An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-u…
Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacE…
Therapeutic Orientation Test in Thrombotic Microangiopathy
Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury
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