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QuickView for hemolytic complement


Curated Studies

Most Correlated Studies

  1. OMIM - Unspecified immunity deficiency
  2. OMIM - Metabolic disease
  3. CD8+ T cells from blood of CD46-deficient patients activated with antibodies against CD3 and CD46
  4. L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
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Literature

Most Relevant Literature

  1. The anaphylatoxin C5a: Structure, function, signaling, physiology, disease, and therapeutics.
  2. Complement Regulation in Human Tenocytes under the Influence of Anaphylatoxin C5a.
  3. Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and…
  4. Characterization of Anaphylatoxin Receptor Expression and C3a/C5a Functions in Anaphylatoxin Recepto…
  5. Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists.
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Clinical Trials

Most Relevant Clinical Trials

  1. Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome …
  2. Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidne…
  3. Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Participants With Aty…
  4. Screening Study to Identify Patients With Complement Factor I Deficiencies
  5. Complement Inhibition in aHUS Dialysis Patients
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