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hiv- 1 protease
Summary
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
PBMCs from HIV patients before and after antiretroviral therapy
Liver tissues from rats after treatment with different compounds
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Most Relevant Literature
Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.
Thermodynamics of strongly allosteric inhibition: a model study of HIV-1 protease.
Binding to the open conformation of HIV-1 protease.
Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application.
Conformational dynamics of HIV-1 protease: a comparative molecular dynamics simulation study with mu…
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Clinical Trials
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Genetics and HIV-1 Protease Inhibitors
Impact of Raltegravir Intensification on HIV-1-infected Subjects With Complete Viral Suppression Und…
A Dose Ranging Study Of GW640385 Boosted With Ritonavir (Rtv) In Comparison To A RTV-Boosted Proteas…
The Pharmacokinetics of Double Boosted Protease Inhibitors in Antiretroviral-naive HIV-1 Infected Pa…
An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combinat…
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