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hops complex
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Liver
Colon cecum
Pituitary gland
Trachea
Skin
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Disease Atlas
Most Correlated Diseases
Pyloric ulcer
Lymphedema
Obsessive-compulsive disorder
Multiple-resistant Staphylococcus aureus infection
Alpha-1-antitrypsin deficiency
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Pharmaco Atlas
Most Correlated Compounds
SB-590885
GSK690693
trinitrophenyl-bovine serum albumin
niguldipine
Apitolisib
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Knockdown Atlas
Most Correlated Gene Perturbations
Idd1
Idd5
INSM2
NUP62
PSCA
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
T regulatory and T effector cells CD3/CD28 stimulation timecourse analysis
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Neural progenitor NPC.CAS9 cells treated with small molecule perturbagens
L1000 CMAP - Breast carcinoma BT20 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
The hookup model of the HOPS complex in autophagosome-lysosome fusion.
Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and…
The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy.
The HOPS complex subunit VPS39 controls ciliogenesis through autophagy.
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane traf…
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Clinical Trials
Most Relevant Clinical Trials
Old SCHOOL Hip-Hop: Improve Alzheimer's Disease Knowledge
Plyometric and Complex Training in Male Cricket Players
Reversal of Dabigatran With Prothrombin Complex Concentrate
Impact of Inhaled PT003 on Complexity and Variability of Tidal Breathing and Oscillatory Mechanics i…
Effect of NT 201 (Botulinum Neurotoxin Type A Free of Complexing Proteins) on Sleep-related Breathin…
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