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QuickView for huntingtin (gene)
Most Relevant Literature
- Peripheral sequestration of huntingtin delays neuronal death and depends on N-terminal ubiquitinatio…
- Interaction between huntingtin exon 1 and HEAT repeat structure probed by chimeric model proteins.
- Lowering mutant huntingtin by small molecules relieves Huntington's disease symptoms and progression…
- Protective Proteolysis in Huntington's Disease: Unraveling the Role of Post-Translational Myristoyla…
- Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas.
Most Relevant Clinical Trials
- N- Homocysteinylated Huntingtin in Huntington's Disease
- iMagemHTT: FIH Evaluation of Novel Mutant Huntingtin PET Radioligands [¹¹C]CHDI-00485180-R and [¹¹C]…
- A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion…
- Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest S…
- HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Developm…
