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QuickView for huntingtin protein
Most Correlated Studies
- Primary E16 striatal neurons expressing wildtype or disease-causing huntingtin protein
- Hypothalamus of N171-82Q model of Huntington's disease euglycemic agent treated
- Brain gene expression in R6/2 Huntington's disease mice treated with a combination drug therapy
- Striatal cell gene expression regulated by TG2 in a transgenic model of Huntington disease (HD)
- Normal or extended glutamine repeat length of HD exon 1 in PC12 model of Huntington's disease
Most Relevant Literature
- Alternative processing of human HTT mRNA with implications for Huntington's disease therapeutics.
- Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility,…
- Differential Effects of Post-translational Modifications on the Membrane Interaction of Huntingtin P…
- Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
- Side chain inset of neurogenerative amino acids to metalloproteins: a therapeutic signature for hunt…
Most Relevant Clinical Trials
- Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest S…
- HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Developm…
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (I…
- A Study to Evaluate the Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)
- A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam…
