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QuickView for hx 630 (compound)


Genetic Markers

Most Correlated Genes

  1. Gm4610
  2. YIPF7
  3. PTPRT
  4. PERM1
  5. PPARGC1A
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. heterocyclic compound binding
  3. organic cyclic compound binding
  4. organic cyclic compound metabolic process
  5. cellular aromatic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. Pituitary tumor AtT20 cells treated with RXR agonist (HX630)
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Literature

Most Relevant Literature

  1. Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression.
  2. Protective effects of retinoid x receptors on retina pigment epithelium cells.
  3. Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse…
  4. 9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiologi…
  5. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model.
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Clinical Trials

Most Relevant Clinical Trials

  1. A Comparison Of Outcomes In Patients In New York Heart Association (NYHA) Class II Heart Failure Whe…
  2. Mortality Due to Malignancy in Patients With Idiopathic Venous Thromboembolism
  3. Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Ver…
  4. Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)
  5. Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Lo…
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