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QuickView for hydroxycholesterol (compound)


Genetic Markers

Most Correlated Genes

  1. CHAC1
  2. DHCR24
  3. TRIB3
  4. SOAT2
  5. LDLR
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Pathway Enrichment

Most Correlated Biogroups

  1. FISCHER_DREAM_TARGETS
  2. GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
  3. MARSON_BOUND_BY_E2F4_UNSTIMULATED
  4. DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP
  5. cytosol
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Curated Studies

Most Correlated Studies

  1. MCF-7 breast adenocarcinoma cells estradiol and 27-Hydroxycholesterol (27HC) treated
  2. 25-hydroxycholesterol effects on human hepatocyte against HCV
  3. Macrophages and epithelial cells from Ch25h knockouts treated with poly I-C or 25-hydroxycholesterol
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Literature

Most Relevant Literature

  1. Effects of 20(S)-hydroxycholesterol on satellite cell proliferation and differentiation of broilers.
  2. Effect of 20(S)-Hydroxycholesterol on Multilineage Differentiation of Mesenchymal Stem Cells Isolate…
  3. Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells.
  4. Elevated hydroxycholesterols in Norwegian patients with hereditary spastic paraplegia SPG5.
  5. Application of Hydroxycholesterols for Alveolar Cleft Osteoplasty in a Rodent Model.
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Clinical Trials

Most Relevant Clinical Trials

  1. Cholesterol and CYP3A4/5 Metabolism Across Pregnancy and Postpartum
  2. 4beta-hydroxycholesterol in Cirrhosis
  3. Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
  4. Efavirenz for Patients With Alzheimer's Disease
  5. Clinical Study to Monitor Plasma Levels of 24OHC in Subject With HD
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