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il17a protein, human
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
SPRR2F
S100A7A
IL36A
SPRR2C
DEFB4B
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
response to stress
response to organic substance
NUYTTEN_EZH2_TARGETS_UP
GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP
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Curated Studies
Most Correlated Studies
Acute monocytic leukemia THP-1 cells treated with IL-17A then sorted for IL-17RC- vs IL-17RC+
Epidermal keratinocytes treated with IFNgamma, IL-4, IL-6, IL-17A and IL-22
Synovial fibroblasts of arthritis patients treated with TNF alone or in combination with IL17
Bronchial epithelial cells in air-liquid interface (ALI) treated with IL-17 and IL-22
IL-17 regulation of keratinocyte gene expression
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Literature
Most Relevant Literature
IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation.
Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint.
Interleukin-17A Promotes Human Disc Degeneration by Inhibiting Autophagy Through the Activation of t…
Optimized methods for IL-17A refolding and anti-IL17A Fab production for co-crystallization with sma…
The role of interchain disulfide bond in a recombinant human interleukin-17A variant.
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Clinical Trials
Most Relevant Clinical Trials
Detection of Circulating Biomarkers of Immunogenic Cell Death
Investigating the Anti-inflammatory Effects of Frondanol in Adults With Inflammatory Bowel Disease
PGE2/IL-22 Pathway in Various Forms of Eczema
Avelumab Plus Intermittent Axitinib in Previously Untreated Patients With Metastatic Renal Cell Carc…
Safety and Efficacy of Adipose Derived Stem Cells in Refractory Rheumatoid Arthritis, Systemic Lupus…
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