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impaired renal function
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
CD46
CFH
EGR1
C3
C1GALT1C1
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
immune response
REACTOME_IMMUNE_SYSTEM
response to stress
regulation of immune response
vesicle
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Curated Studies
Most Correlated Studies
Whole blood expression profiles of uremic patients
CD4+ T cells from an atypical hemolytic uremic syndrome (aHUS) patient carrying mutant CD46
Kidneys with AKI and Drosha knockdown - mesenchymal stromal cells or extracellular vesicles treated
CD8+ T cells from blood of CD46-deficient patients activated with antibodies against CD3 and CD46
Kidneys from renal ablation CKD mouse model treated with aliskiren and losartan.
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Literature
Most Relevant Literature
Renin-Angiotensin-Aldosterone System Inhibitions and Cardiovascular Outcomes in Acute Myocardial Inf…
Renal impairment and mortality in patients with STEMI and cardiogenic shock/cardiac arrest.
Co-exposure of petrochemical workers to noise and mixture of benzene, toluene, ethylbenzene, xylene,…
Teclistamab in patients with multiple myeloma and impaired renal function.
Impact of renal impairment on dihydropyrimidine dehydrogenase (DPD) phenotyping.
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Clinical Trials
Most Relevant Clinical Trials
Computer Prescribing System and Impaired Renal Function
Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions
Study of Aldafermin (NGM282) in Participants With Impaired Renal Function
A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function
Evaluate PK and Safety of Proellex® in Females With Various Stages of Impaired Renal Function and He…
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