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interferon type i
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General Info
Genetic Markers
Most Correlated Genes
RSAD2
IFIT1
MX1
CXCL10
IFI44L
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Pathway Enrichment
Most Correlated Biogroups
GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN
GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN
GSE42021_TREG_VS_TCONV_PLN_UP
GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP
GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP
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Curated Studies
Most Correlated Studies
Anti-FcgRIIb-treated dendritic cells and monocytes
Influenza virus infection-induced gene expression changes of regional B cells
PBMCs from hepatitis C patients undergoing peg-interferon alfa 2b and ribavirin therapy
Gene expression in macrophages treated with IFNalpha
BE(2)-C neuronal responses to type I IFN stimulation and western equine encephalitis virus infection
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Literature
Most Relevant Literature
CNS disease associated with enhanced type I interferon signalling.
Differential signaling by type-I and type-III interferons in mucosa.
Type I interferon pathway genetic variants in severe COVID-19.
Assessment of type I interferon response in routine practice in France in 2022.
Unweaving type I interferons in age-related neuroinflammation.
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Clinical Trials
Most Relevant Clinical Trials
Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I
Pronostic Value of Type I ANTi-Interferon Antibodies in Patients With COVID-19 Acute Respiratory Fai…
Type I Interferon Alfa-2a in Postmastectomy Breast Reconstruction
A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases
A Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Anifrolumab in Adult T…
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