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interleukin 12 subunit p35
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
IL2
TNFSF14
GZMB
MIPEP
SGSH
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Pathway Enrichment
Most Correlated Biogroups
GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP
GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN
GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN
GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN
PUJANA_CHEK2_PCC_NETWORK
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Curated Studies
Most Correlated Studies
NK cell gene expression in response to activation by mycobacteria of differing virulence
Th1 or Th2 in the presence or absence of TGFbeta
L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Pyruvate Kinase M2 Promotes the Activation of Dendritic Cells by Enhancing IL-12p35 Expression.
The characterization of an interleukin-12 p35 homolog involved in the immune modulation of oyster Cr…
Interleukin-12p35 deficiency enhances mitochondrial dysfunction and aggravates cardiac remodeling in…
The difference in immune response and IL-12p35 methylation between newborns and adults.
Neutrophil functions can be regulated by IL-35, which is mainly expressed in IL-15Rα+ cells in grass…
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Clinical Trials
Most Relevant Clinical Trials
IL-10, IL-12 and IL-18 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and He…
A Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics…
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