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irinotecan
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
ACKR3
OLFML2B
VCAM1
COL11A1
GAL
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Pathway Enrichment
Most Correlated Biogroups
cell periphery
cell differentiation
enzyme binding
BLALOCK_ALZHEIMERS_DISEASE_DN
regulation of transport
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Curated Studies
Most Correlated Studies
Gastroesophegeal tumors and adjacent normal tissues before and after chemotreatment
Colon cancer HT 115 cells expressing UGT1A isoform 2 shRNA and treated with SN-38
Metastatic colorectal tumors from responder and nonresponder patients undergoing the FOLFIRI regimen
Colorectal cancer drug-sensitive parental cell lines and chemotherapy-resistant sub cell lines
Squamous cervical carcinoma patients after neoadjuvant chemotherapy - responders and non-responders
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Literature
Most Relevant Literature
UGT1A1 genotype-guided dosing of irinotecan: time to prioritize patient safety.
Synergistic cytotoxicity of irinotecan combined with polysaccharide-based nanoparticles for colorect…
Development and Evaluation of Biotin Functionalized Fullerenes for the Delivery of Irinotecan to Col…
Recent advances in SN-38 drug delivery system.
Effects of common genetic variants of human uridine diphosphate glucuronosyltransferase subfamilies …
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Clinical Trials
Most Relevant Clinical Trials
Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer…
Study of MLN8237 in Combination With Irinotecan and Temozolomide
Venetoclax and Irinotecan in Relapsed/Refractory SCLC
Clinical and Pharmacokinetic Trial of Intra-Abdominal Irinotecan
A Protocol of Irinotecan for Carcinoma of the Lung
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