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jak2 protein, human
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Summary
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Genetic Markers
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Pathway Enrichment
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No biogroups found
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Curated Studies
Most Correlated Studies
Bone marrow of B-cell precursor acute lymphoblastic leukemic children with PAX5-related gene fusions
Lung cancer NCI-H1573, NCI-H1992, NCI-H596 cells treated with Crizotinib, IFN gamma and HGF
Lung fibroblast IMR-90 cells treated with oncostatin M
Erythroleukemia cells (TF-1) overexpressing GNB1 K89E 12hr post GM-CSF withdrawal
CML K-562 cells overexpressing wildtype or mutant CALR and treated with melittin
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Literature
Most Relevant Literature
New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation.
Increased Risk of Thoracic Aortic Aneurysms With JAK2 V617F.
Rare Causes of Acute Coronary Syndrome: The JAK2 V617F Mutation-Positive Myeloproliferative Neoplasm…
Molecular basis of JAK2 H608Y and H608N mutations in the pathology of acute myeloid leukemia.
EnvIRONment modifies polycythemia vera.
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Clinical Trials
Most Relevant Clinical Trials
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloprolifer…
Growth Hormone Signaling in Vivo in Humans
The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies
Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal …
A Study to Evaluate Safety and Efficacy of Panobinostat in Participants With Primary Myelofibrosis
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