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kainate
(compound)
Summary
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Genetic Markers
Most Correlated Genes
FOS
FOSB
NPAS4
ATF3
GADD45G
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Pathway Enrichment
Most Correlated Biogroups
HALLMARK_TNFA_SIGNALING_VIA_NFKB
WONG_ADULT_TISSUE_STEM_MODULE
BLALOCK_ALZHEIMERS_DISEASE_DN
MODULE_1
regulation of nitrogen compound metabolic process
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Curated Studies
Most Correlated Studies
Neural 3D tissue constructs from H1 ESC-derived precursor cells treated with neurotoxic chemicals
Kainate-induced neuronal death
Effect of loss of CREB1 and CREM on expression in the brain induced by strong stimulation
Dorsal hippocampi of C57Bl/6j mice treated with kainate to induce mesio-temporal lobe epilepsy
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Literature
Most Relevant Literature
Topiramate reduces excitability in the basolateral amygdala by selectively inhibiting GluK1 (GluR5) …
Kainate induces various domain closures in AMPA and kainate receptors.
Neu2000 potentiates a kainate response in mouse cortical neurons.
Mapping kainate activation of inner neurons in the rat retina.
Intermittent hypobaric hypoxia induces neuroprotection in kainate-induced oxidative stress in rats.
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Clinical Trials
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Evaluation of a Novel Positron Emission Tomography (PET Radiotracer for TARP Gamma-8
Clinical Utility of Pharmacogenomics of Psychotropic Medications
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
Topiramate in the Treatment of Sciatica
Brain Imaging, Genetics and Treatment for Major Depression
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