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kinase lck
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Curated Studies
Most Correlated Studies
Gene expression profile of basal signaling in T cells.
Brain tumors from mice grafted with human glioma cells and LCK inhibitor-treated
Gene expression in splenic tumors derived from mice injected with Bfl-1DC p53DD transfected cells
Splenic and Lymphatic T-cell gene expression of wildtype and MEKK2/MEKK3 double knockout mice
T-ALL KHYG1 control or DOCK8 knockout cells activated with anti-NKp30
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Literature
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Novel role for p56/Lck in regulation of endothelial cell survival and angiogenesis.
P56(lck) kinase inhibitor studies: a 3D QSAR approach towards designing new drugs from flavonoid der…
Conformational states of the kinase Lck regulate clustering in early T cell signaling.
TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) re…
Modulation of Kv1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-…
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Clinical Trials
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A Phase I Study of AZD0424 Alone and in Combination in Advanced Solid Tumours
Phase II Dasatinib Study in Advanced Breast Cancer
Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers
Immunomodulating Therapy and Improved Vaccination Responses by Cox-2 Inhibitor in HIV-infected Patie…
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma Patients
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