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QuickView for lamivudine (compound)


Genetic Markers

Most Correlated Genes

  1. ESPL1
  2. CYP2E1
  3. SPP2
  4. FGF9
  5. CIT
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. response to organic substance
  3. cytosol
  4. response to stress
  5. nucleoplasm
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Curated Studies

Most Correlated Studies

  1. Adipose tissue of HIV+ patients undergoing different anti-viral treatments
  2. Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
  3. Drug target sets for approved compounds
  4. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
  5. Liver Pharmacology and Xenobiotic Response Repertoire
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Literature

Most Relevant Literature

  1. Assessment of complex genomic alterations induced by AZT, 3TC, and the combination AZT +3TC.
  2. To dose-adjust or not to dose-adjust: 3TC dose in kidney impairment.
  3. Switching to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF) Maintains HIV-1 Virol…
  4. A long-acting 3TC ProTide nanoformulation suppresses HBV replication in humanized mice.
  5. Lamivudine salts with improved solubilities.
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Clinical Trials

Most Relevant Clinical Trials

  1. Atazanavir/r + Lamivudine Dual Therapy
  2. Lamivudine for Chronic Hepatitis B
  3. Resistance to Lamivudine in HBV Egyptian Patients
  4. Lamivudine and Adefovir Dipivoxil Fixed Dose Combination
  5. Comparison Between Lamivudine and Entecavir Treatment in Spontaneous Severe Acute Exacerbation
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