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lestaurtinib
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Summary
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Genetic Markers
Most Correlated Genes
HBB
HOXC6
CD24
MAL
PAPPA
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Pathway Enrichment
Most Correlated Biogroups
FISCHER_DREAM_TARGETS
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DODD_NASOPHARYNGEAL_CARCINOMA_DN
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP
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Curated Studies
Most Correlated Studies
Prostate adenocarcinoma LNCaP cells with PKN1 inhibition treated with R1881
Human erythroleukemia cells treated with CEP701 or PRMT5-knockdown
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats.
Ponatinib, Lestaurtinib, and mTOR/PI3K Inhibitors Are Promising Repurposing Candidates against Entam…
FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymp…
Lestaurtinib potentiates TRAIL-induced apoptosis in glioma via CHOP-dependent DR5 induction.
Lestaurtinib is a potent inhibitor of anaplastic thyroid cancer cell line models.
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Clinical Trials
Most Relevant Clinical Trials
CEP-701 (Lestaurtinib) in Myelofibrosis
Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Ac…
Open-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thro…
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagno…
Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia
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