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QuickView for leukotrienes (compound)


Genetic Markers

Most Correlated Genes

  1. EGR3
  2. CCL4
  3. EGR2
  4. FOSB
  5. PHLDA1
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Pathway Enrichment

Most Correlated Biogroups

  1. HALLMARK_TNFA_SIGNALING_VIA_NFKB
  2. NAGASHIMA_NRG1_SIGNALING_UP
  3. GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP
  4. GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN
  5. NAGASHIMA_EGF_SIGNALING_UP
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Curated Studies

Most Correlated Studies

  1. Liver Pharmacology and Xenobiotic Response Repertoire
  2. Livers of rat exposed to variety of hepatotoxic compounds
  3. Human mast LAD2 and LUVA cells treated with leukotriene D4 or E4
  4. Peripheral blood monocytes treated with leukotriene B4
  5. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
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Literature

Most Relevant Literature

  1. Cysteinyl Leukotrienes in Allergic Inflammation.
  2. Histamine and TH2 cytokines regulate the biosynthesis of cysteinyl-leukotrienes and expression of th…
  3. Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 rece…
  4. Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targ…
  5. Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control.
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Clinical Trials

Most Relevant Clinical Trials

  1. Leukotriene D4 Nasal Provocation Test in Allergic Rhinitis
  2. Leukotriene D4 Bronchial Provocation Test (LTD4-BPT) as an Indicator for the Use of Leukotriene Rece…
  3. Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity
  4. Targeting Leukotrienes in Kidney Disease
  5. The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19)
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