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QuickView for ligase iv (gene)


Body Atlas

Most Correlated Tissues

  1. Thymus gland
  2. Basophil of peripheral blood
  3. Neutrophil of bone marrow
  4. Leukocyte (polymorphonuclear) of peripheral blood
  5. Eosinophil of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Multiple myeloma/plasmacytoma
  2. Cytomegalovirus infection
  3. Allergy to substance
  4. Huntington's disease
  5. Rift valley fever
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Pharmaco Atlas

Most Correlated Compounds

  1. PI103
  2. ethotoin
  3. Puromycin Aminonucleoside
  4. Neupogen
  5. lumicolchicine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR210
  2. XRN2
  3. TNFRSF1A
  4. LIG4
  5. SPINK1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Double-strand break repair plays a role in repeat instability in a fragile X mouse model.
  2. Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells …
  3. Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic…
  4. Polymorphisms of DNA repair genes XRCC1 and LIG4 and idiopathic male infertility.
  5. Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.
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Clinical Trials

Most Relevant Clinical Trials

  1. Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases
  2. Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
  3. A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excret…
  4. Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Adva…
  5. Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer
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