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map kinase kinase kinase 2
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
No genes found
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Pathway Enrichment
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No biogroups found
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Allicin regulates Treg/Th17 balance in mice with collagen-induced arthritis by increasing the expres…
A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program.
Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2.
Case studies showing clinical signs and management of cutaneous toxicity of the MEK1/2 inhibitor AZ…
Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.
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Clinical Trials
Most Relevant Clinical Trials
Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor…
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Hu…
Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With…
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzhe…
A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer'…
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