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mcl1 protein, human
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Genetic Markers
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Curated Studies
Most Correlated Studies
Breast cancer MDA-MB-468, MDA-MB-231, and MDA-MB-157 cells with thalidomide, BETi-211, or BETd-246
T cell acute lymphoblastic leukemia cells with JDP2 shRNA knockdown
Breast adenocarcinoma MDA-MB-468 cells with PRPF8 or PRPF38A siRNA knockdown or treated with E7107
Lung cancer A549 and Calu-6 cells treated with pimasertib
Chronic lymphocytic leukemia cells treated with CDKI-73 and fludarabine
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Literature
Most Relevant Literature
GSK3β suppression inhibits MCL1 protein synthesis in human acute myeloid leukemia cells.
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
β2-adrenoreceptor Signaling Increases Therapy Resistance in Prostate Cancer by Upregulating MCL1.
Structural revision of the Mcl-1 inhibitor MIM1: synthesis and biological studies on ovarian cancer …
Saga of Mcl-1: regulation from transcription to degradation.
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Clinical Trials
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AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Partic…
VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed…
Study of the Metabolism in the Lymphatic Niche of CLL
Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometri…
Ixazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapse…
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