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QuickView for mitochondrial pyruvate dehydrogenase complex (biogroup)


Body Atlas

Most Correlated Tissues

  1. Heart
  2. Heart atrium
  3. Lung
  4. Adipose tissue subcutaneous
  5. Heart ventricle
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Disease Atlas

Most Correlated Diseases

  1. Disorder affecting transplanted structure
  2. Bovine respiratory syncytial virus disease
  3. Injury of liver
  4. Viral infections of the central nervous system
  5. Pyruvate dehydrogenase complex deficiency
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Pharmaco Atlas

Most Correlated Compounds

  1. 2-aminoacetophenone
  2. lornoxicam
  3. LG 100268
  4. shikonin
  5. Cardiotoxin I
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Mir21a
  2. MAP2K3
  3. ELN
  4. CACNA1C
  5. GMEB2
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Curated Studies

Most Correlated Studies

  1. Adipocyte profiling analyses of Selective PPARg Modulators and full PPARg agonists
  2. Expression profiles of DGAT1 and DGAT2 double KO and wildtype adipocytes
  3. L1000 CMAP Prostate cancer PC3 cells with gene overexpression perturbations (1 of 2)
  4. Differentiated adipocytes depleted of various long non-coding RNAs
  5. Lacrimal Gland Gene expression in Aromatase Knockout Mice and Wild Type Controls
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Literature

Most Relevant Literature

  1. Scanning mutagenesis" of the amino acid sequences flanking phosphorylation site 1 of the mitochondri…
  2. A mutation in the E2 subunit of the mitochondrial pyruvate dehydrogenase complex in Arabidopsis redu…
  3. Pyruvate dehydrogenase-e1α deficiency presenting as recurrent demyelination: an unusual presentation…
  4. Quantitative proteome of medulla oblongata in spontaneously hypertensive rats.
  5. Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Me…
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Clinical Trials

Most Relevant Clinical Trials

  1. Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies
  2. Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:
  3. Natural History Study of Pyruvate Dehydrogenase Deficiency
  4. Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
  5. Mitochondrial Energy Production in ART (Assisted Reproductive Technology )
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