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QuickView for ms 275 (compound)


Genetic Markers

Most Correlated Genes

  1. RGS4
  2. HPCAL4
  3. RSAD2
  4. NGFR
  5. CALB1
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Pathway Enrichment

Most Correlated Biogroups

  1. cellular aromatic compound metabolic process
  2. heterocycle metabolic process
  3. organic cyclic compound metabolic process
  4. nucleoplasm
  5. heterocyclic compound binding
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Curated Studies

Most Correlated Studies

  1. Pancreatic cell lines treated with chromatin-targeting small molecules
  2. TBV2 embryonic stem cells stimulated with Class I HDAC inhibitor MS-275
  3. Esophageal cancer cell line response to single or combined azacytidine and MS-275 treatments
  4. Plasma cell leukemia L-363 cells treated with rapamycin and MS-275 alone or in combination
  5. Colorectal cancer Caco-2et cells with dox-induced KRAS G12V mutation and with MS-275
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Literature

Most Relevant Literature

  1. In Vivo Two-Photon Imaging Analysis of Dynamic Degradation of Hepatic Lipid Droplets in MS-275-Treat…
  2. MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.
  3. HDAC inhibitor, MS-275, increases vascular permeability by suppressing Robo4 expression in endotheli…
  4. The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates …
  5. The histone deacetylase inhibitor, entinostat (MS-275), induces the odontogenic differentiation of a…
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Clinical Trials

Most Relevant Clinical Trials

  1. Memantine for Spasticity in MS Patients
  2. The MS-LINK™ Outcomes Study
  3. Next-Gen MS: Feed-forward PRO Data for MS Research
  4. JC Virus Antibody Study of Participants With Relapsing Forms of MS Receiving Treatment With Natalizu…
  5. Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma
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