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QuickView for nicotinic agonists (compound)


Genetic Markers

Most Correlated Genes

  1. CYP1A1
  2. KCNB1
  3. CHRNA2
  4. CYP1B1
  5. GPX3
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Pathway Enrichment

Most Correlated Biogroups

  1. heterocyclic compound binding
  2. organic cyclic compound binding
  3. heterocycle metabolic process
  4. organic cyclic compound metabolic process
  5. PILON_KLF1_TARGETS_DN
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Curated Studies

Most Correlated Studies

  1. Effects of nicotine on the palate development
  2. Oral keratinocytes treated with ethanol and nicotine
  3. Prostate cancer cell lines treated with nicotine
  4. Prostate of TRAMP mice exposed to nicotine
  5. Liver, breast and endometrial cell lines exposed to 34 toxicological compounds
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Literature

Most Relevant Literature

  1. The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acu…
  2. Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with d…
  3. Partial agonists for α4β2 nicotinic receptors stimulate dopaminergic neuron firing with relatively e…
  4. A fluorinated quinuclidine benzamide named LMA 10203 acts as an agonist of insect nicotinic acetylch…
  5. The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus …
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Clinical Trials

Most Relevant Clinical Trials

  1. Parkinson's Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug
  2. Phase 2 Trial of a Nicotinic Agonist in Schizophrenia
  3. Nicotinic Agonist Effects on BMI and Neuronal Response
  4. Phase I Nicotinic Agonist Treatment Trial for Autism
  5. Safety and Efficacy of the Novel Selective Nicotinic Receptor Partial Agonist, CHANTIX (Varenicline)…
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