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nicotinic antagonists
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CHRNA2
CHRM2
CHRNA10
ATP2A3
ATF3
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Pathway Enrichment
Most Correlated Biogroups
neuron projection
regulation of nitrogen compound metabolic process
response to organic substance
organic cyclic compound binding
heterocyclic compound binding
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Curated Studies
Most Correlated Studies
C. elegans L1 larvae exposed to EtBr and/or serial UVC radiation
B-cell lymphoma cell lines treated by 92 FDA approved compounds - a timecourse
Drug Matrix In Vivo Toxicogenomic Study - Rat Heart [Codelink]
Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
Drug target sets for approved compounds
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Literature
Most Relevant Literature
Validation of a high-throughput, automated electrophysiology platform for the screening of nicotinic…
Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies wi…
Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist.
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice.
Modulation of peripheral inflammatory pain thresholds by M(1) and nicotinic receptor antagonists.
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Clinical Trials
Most Relevant Clinical Trials
Nicotinic Modulation of the Default Network
Effects of Prazosin on the Attention-Enhancing Effects of Nicotine
Effects of Naltrexone on Nicotine Reinforcement
Nicotinic Modulation of the Default Network of Resting Brain Function
Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia
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