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QuickView for nifurtimox (compound)


Genetic Markers

Most Correlated Genes

  1. IFNAR2
  2. KRAS
  3. PARD6B
  4. PGK1
  5. MED12L
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Pathway Enrichment

Most Correlated Biogroups

  1. FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS
  2. HALLMARK_P53_PATHWAY
  3. CHEN_METABOLIC_SYNDROM_NETWORK
  4. protein transport
  5. peptide transport
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Curated Studies

Most Correlated Studies

  1. Broad Connectivity Map (CMAP 2.0) compound database
  2. Lung cancer A549 cells treated with anti-influenza virus agent nifurtimox and chrysin
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Literature

Most Relevant Literature

  1. Selected Aspects of the Analytical and Pharmaceutical Profiles of Nifurtimox.
  2. Melt crystallization and thermal degradation profile of the antichagasic drug nifurtimox.
  3. Solid-state properties of Nifurtimox. Preparation, analytical characterization, and stability of an …
  4. Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox.
  5. In vivo Metabolism of Nifurtimox and the Drug-Drug Interaction Potential Including its Major Metabol…
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Clinical Trials

Most Relevant Clinical Trials

  1. Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' Disease
  2. Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma
  3. Nifurtimox Versus Benznidazole Effectiveness and Tolerance for Chagas Disease Treatment
  4. Study Will Evaluate the Relative Bioavailability, Safety, and Tolerability of Single Doses of Nifurt…
  5. Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' Pat…
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